Changing Paradigm in Acute Stroke Management

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J Neurol Stroke 2017, 6(4): 00206 Thrombolysis (PROACT) followed by the PROACT II [3] have laid the foundation for IA-thrombolysis. Recanalization in the range of 66%, complete Recanalization (Thrombolysis in Myocardial Infarction [TIMI] grade 3) in 19% and improved outcome with IA-thrombolysis made it a definite advantage over IV rt-PA. Despite higher recanalization rates, the relative unpredictability of this form of treatment led to search for better tools to treat acute stroke. Combined clot disruption and IA-thrombolysis were initiated in the clinical setting by Barnwell et al. [4]. This early experience underscored the need for safe and reliable clot retrieval systems.

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تاریخ انتشار 2017